From Diabetes Each day:

Metformin is the world’s most-prescribed diabetes drug. For a technology, most People with newly identified kind 2 diabetes have been prescribed metformin as their first medicine.

However now metformin’s reign because the universally acknowledged “first-line” therapy for kind 2 diabetes has come to an finish. Up to date steering from the American Diabetes Affiliation (ADA), launched on December 12, 2022, has considerably minimized the significance of the favored drug. The ADA’s committee of specialists eliminated metformin from key suggestions and now ranks the drug as inferior to different choices for blood sugar management, weight reduction, and long-term coronary heart and kidney safety

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The brand new ADA advice might be seen as a significant endorsement for the celebrities of the latest technology of diabetes medicine: SGLT-2 inhibitors and GLP-1 and GIP/GLP-1 receptor agonists. These choices fight hyperglycemia successfully however add different essential advantages that metformin can’t declare: enhanced weight reduction and extra sturdy safety towards cardiovascular and kidney illness.

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Steve Parker, M.D.