Semaglutide and liraglutide are medicine that have been developed to deal with diabetes and are FDA-approved for that. They’re given by subcutaneous injection. Semaglutide can also be FDA-approved for weight reduction in non-diabetics if sure situations are met.

As soon as-weekly semaglutide outperformed each day liraglutide in obese and overweight non-diabetics.

From JAMA Community:

Query Amongst adults with obese or weight problems with out diabetes, what’s the impact of once-weekly subcutaneous semaglutide, 2.four mg, vs once-daily subcutaneous liraglutide, three.zero mg, on weight reduction when every is added to counseling for weight loss plan and bodily exercise?

Findings On this randomized medical trial that included 338 individuals, imply physique weight change from baseline to 68 weeks was –15.eight% with semaglutide vs –6.four% with liraglutide, a statistically vital distinction.

Which means Amongst adults with obese or weight problems with out diabetes, once-weekly subcutaneous semaglutide, in contrast with once-daily subcutaneous liraglutide, added to counseling for weight loss plan and bodily exercise resulted in considerably better weight reduction at 68 weeks.

For prevention or enchancment of overweight- and obesity-related diseases, intention for lack of at the very least 5 to 10% of physique weight. Assuming you’re obese or overweight within the first place. 16% physique weight change is important. 16% of 300 kilos (136 kg) can be 48 kilos (22 kg).

Steve Parker, M.D.

PS: My guide’s inexpensive than these medicine. And no needles!